Vaccins de pointe

NEW YORK – L’invention des vaccins compte parmi les plus grandes réussites de l’histoire de la santé publique et individuelle. Ils ont permis d’éliminer de la surface de la planète des fléaux comme la variole, ils sont sur le point d’éliminer la poliomyélite et chaque année sauve la vie de millions de personnes, réduisant les souffrances et les coûts causés par des maladies infectieuses.

Mais il reste un grand nombre de maladies pour lesquelles des vaccins n’existent pas encore. De plus, il est peu probable que des stratégies de mise au point de vaccins qui ont réussi auparavant puissent fonctionner contre des bactéries ou des virus plus complexes, comme le VIH, qui ont développé des mécanismes multiples pour éviter le système immunitaire.

L’histoire de la vaccinologie en est une où les progrès biomédicaux et technologiques pourraient annoncer la « prochaine génération » de vaccins. Dans les années 1950, une percée a permis la culture de virus dans des cultures tissulaires ; ce qui a rendu possible la mise au point de vaccins vivants atténués et des vaccins inactivés contre la rougeole, la poliomyélite et d’autres maladies. Dans les années 1980, la technologie de recombinaison de l’ADN a mené à la mise au point de vaccins contre l’hépatite B et le virus du papillome humain.

To continue reading, please log in or enter your email address.

Registration is quick and easy and requires only your email address. If you already have an account with us, please log in. Or subscribe now for unlimited access.

required

Log in

http://prosyn.org/EBNjahU/fr;
  1. Sean Gallup/Getty Images

    Angela Merkel’s Endgame?

    The collapse of coalition negotiations has left German Chancellor Angela Merkel facing a stark choice between forming a minority government or calling for a new election. But would a minority government necessarily be as bad as Germans have traditionally thought?

  2. Trump Trade speech Bill Pugliano/Getty Images .

    Preparing for the Trump Trade Wars

    In the first 11 months of his presidency, Donald Trump has failed to back up his words – or tweets – with action on a variety of fronts. But the rest of the world's governments, and particularly those in Asia and Europe, would be mistaken to assume that he won't follow through on his promised "America First" trade agenda.

  3. A GrabBike rider uses his mobile phone Bay Ismoyo/Getty Images

    The Platform Economy

    While developed countries in Europe, North America, and Asia are rapidly aging, emerging economies are predominantly youthful. Nigerian, Indonesian, and Vietnamese young people will shape global work trends at an increasingly rapid pace, bringing to bear their experience in dynamic informal markets on a tech-enabled gig economy.

  4. Trump Mario Tama/Getty Images

    Profiles in Discouragement

    One day, the United States will turn the page on Donald Trump. But, as Americans prepare to observe their Thanksgiving holiday, they should reflect that their country's culture and global standing will never recover fully from the wounds that his presidency is inflicting on them.

  5. Mugabe kisses Grace JEKESAI NJIKIZANA/AFP/Getty Images

    How Women Shape Coups

    In Zimbabwe, as in all coups, much behind-the-scenes plotting continues to take place in the aftermath of the military's overthrow of President Robert Mugabe. But who the eventual winners and losers are may depend, among other things, on the gender of the plotters.

  6. Oil barrels Ahmad Al-Rubaye/Getty Images

    The Abnormality of Oil

    At the 2017 Abu Dhabi Petroleum Exhibition and Conference, the consensus among industry executives was that oil prices will still be around $60 per barrel in November 2018. But there is evidence to suggest that the uptick in global growth and developments in Saudi Arabia will push the price as high as $80 in the meantime.

  7. Israeli soldier Menahem Kahana/Getty Images

    The Saudi Prince’s Dangerous War Games

    Saudi Arabia’s Crown Prince Mohammed bin Salman is working hard to consolidate power and establish his country as the Middle East’s only hegemon. But his efforts – which include an attempt to trigger a war between Israel and Hezbollah in Lebanon – increasingly look like the work of an immature gambler.