突破疫苗

纽约—疫苗是个人和公共健康史上最伟大的成功之一。它们帮助地球摆脱了天花,即将消灭脊髓灰质炎,并且每一年能挽救数百万人的生命,减轻传染病造成的痛苦和负担。

但仍有许多疾病我们没有疫苗可用。此外,早前带来成功疫苗开发的策略不再适用于更加复杂的细菌和病毒,比如可通过多种机制削弱免疫系统的艾滋病毒。

疫苗学的历史是一部生物化学和技术进步带来“下一代”疫苗的历史。20世纪50年代,能让病毒在培养基中生长的突破带来了麻疹、脊髓灰质炎和其他疾病的减毒活疫苗和灭活疫苗的发展。20世纪80年代,DNA重组技术带来了乙肝和人乳头瘤病毒疫苗的发展。

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