Wally Gobetz/Flickr

Die Sequenzierung eines Vampir-Genoms

NEW HAVEN – Die Afrikanische Trypanosomiasis – auch als Schlafkrankheit bekannt – ist seit langem eine Geißel der Menschen in Afrika südlich der Sahara. Bei der Krankheit handelt es sich um eine parasitäre Infektion, die unbehandelt vielfach zum Tod führt. Und die Behandlung dieser Krankheit ist komplex und bedarf genau jener Art von hochqualifiziertem medizinischem Personal, das in betroffenen Gebieten so schwer zu finden ist. Die Parasiten, die zu den Infektionen führen - Trypanosoma brucei gambiense in Zentral- und Westafrika sowie T. b. rhodesiense in Ostafrika – werden durch den Biss einer infizierten Tsetsefliege (Glossina morsitans morsitans) übertragen.

Im frühen 20. Jahrhundert sorgten Trypanosomiasis-Epidemien für eine Dezimierung der Bevölkerung in vielen Teilen Afrikas. Obwohl systematische Früherkennungsprogramme und die Behandlung von Millionen Menschen die Übertragung der Krankheit in den 1930er Jahren drastisch reduzierten, führte die Lockerung dieser Bestrebungen in den 1950er und 1960er Jahren zu einer Wiederkehr der Krankheit, deren Ausbreitung in den frühen 1990er Jahren epidemische Ausmaße annahm. Aufgrund einer Kampagne der Weltgesundheitsorganisation brachte man die Krankheit schließlich im Jahr 2008 unter Kontrolle, wobei es mittlerweile lediglich 10.000 Neuerkrankungen pro Jahr gibt. Doch Millionen Menschen bleiben dem Risiko weiterhin ausgesetzt.

Offenkundig stellt die Tsetsefliege eine ernsthafte Gefahr in jenen Gebieten dar, wo der Zugang zur Behandlung am schlechtesten ist und wo man sie sich auch am wenigsten leisten kann. Bedroht sind überdies nicht nur Menschen. Die afrikanische Trypanosomiasis bei Tieren, auch als Nagana-Krankheit bezeichnet, wird von den Parasiten Trypanosoma congolense, T. vivax, und T. brucei verursacht – die ebenfalls alle von der Tsetsefliege übertragen werden.

To continue reading, please log in or enter your email address.

Registration is quick and easy and requires only your email address. If you already have an account with us, please log in. Or subscribe now for unlimited access.


Log in

  1. Television sets showing a news report on Xi Jinping's speech Anthony Wallace/Getty Images

    Empowering China’s New Miracle Workers

    China’s success in the next five years will depend largely on how well the government manages the tensions underlying its complex agenda. In particular, China’s leaders will need to balance a muscular Communist Party, setting standards and protecting the public interest, with an empowered market, driving the economy into the future.

  2. United States Supreme Court Hisham Ibrahim/Getty Images

    The Sovereignty that Really Matters

    The preference of some countries to isolate themselves within their borders is anachronistic and self-defeating, but it would be a serious mistake for others, fearing contagion, to respond by imposing strict isolation. Even in states that have succumbed to reductionist discourses, much of the population has not.

  3.  The price of Euro and US dollars Daniel Leal Olivas/Getty Images

    Resurrecting Creditor Adjustment

    When the Bretton Woods Agreement was hashed out in 1944, it was agreed that countries with current-account deficits should be able to limit temporarily purchases of goods from countries running surpluses. In the ensuing 73 years, the so-called "scarce-currency clause" has been largely forgotten; but it may be time to bring it back.

  4. Leaders of the Russian Revolution in Red Square Keystone France/Getty Images

    Trump’s Republican Collaborators

    Republican leaders have a choice: they can either continue to collaborate with President Donald Trump, thereby courting disaster, or they can renounce him, finally putting their country’s democracy ahead of loyalty to their party tribe. They are hardly the first politicians to face such a decision.

  5. Angela Merkel, Theresa May and Emmanuel Macron John Thys/Getty Images

    How Money Could Unblock the Brexit Talks

    With talks on the UK's withdrawal from the EU stalled, negotiators should shift to the temporary “transition” Prime Minister Theresa May officially requested last month. Above all, the negotiators should focus immediately on the British budget contributions that will be required to make an orderly transition possible.

  6. Ksenia Sobchak Mladlen Antonov/Getty Images

    Is Vladimir Putin Losing His Grip?

    In recent decades, as President Vladimir Putin has entrenched his authority, Russia has seemed to be moving backward socially and economically. But while the Kremlin knows that it must reverse this trajectory, genuine reform would be incompatible with the kleptocratic character of Putin’s regime.

  7. Right-wing parties hold conference Thomas Lohnes/Getty Images

    Rage Against the Elites

    • With the advantage of hindsight, four recent books bring to bear diverse perspectives on the West’s current populist moment. 
    • Taken together, they help us to understand what that moment is and how it arrived, while reminding us that history is contingent, not inevitable

    Global Bookmark

    Distinguished thinkers review the world’s most important new books on politics, economics, and international affairs.

  8. Treasury Secretary Steven Mnuchin Bill Clark/Getty Images

    Don’t Bank on Bankruptcy for Banks

    As a part of their efforts to roll back the 2010 Dodd-Frank Act, congressional Republicans have approved a measure that would have courts, rather than regulators, oversee megabank bankruptcies. It is now up to the Trump administration to decide if it wants to set the stage for a repeat of the Lehman Brothers collapse in 2008.