Medical equipment

Revolusi Pelayanan Kesehatan di Timur Tengah

KAIRO – Pada kunjungan terkini ke Yordania dan Mesir, sebagai bagian dari misi dagang yang dipimpin oleh Departemen Perdagangan Amerika Serikat, saya terkesan dengan potensi kawasan tersebut untuk menjadi pusat pengobatan yang terdepan. Dengan menggabungkan kebijakan yang tepat dan kemauan politik yang cukup, Timur Tengah bisa menjadi kawasan penting di dunia dalam hal penelitian pelayanan kesehatan. Pada khususnya, kawasan ini memiliki peran penting terkait dengan uji klinis mengenai farmasi yang dirancang untuk memeriksa pengaruh garis keturunan pasien terhadap keamanan, manfaat, dan efektivitas pengobatan.

Seiring dengan meningkatnya pemahaman kita akan genetika, semakin jelas bahwa garis keturunan kita berperan dalam menentukan khasiat obat-obatan tertentu. Misalnya, banyak studi menunjukkan bahwa pasien keturunan Eropa merespon beta blockers dan ACE inhibitors lebih baik dibandingkan pasien keturunan Afrika. Asal-usul benua (continental origins) sering menjadi pertimbangan dalam pemilihan pengobatan tekanan darah tinggi dan obat kardiovaskuler yang optimal.

Contoh lainnya adalah warfarin, obat antikoagulan. Sebuah penelitian menemukan bahwa para pasien keturunan Afrika membutuhkan dosis lebih tinggi daripada mereka yang keturunan Eropa; pasien dengan nenek moyang dari Asia membutuhkan dosis yang lebih rendah. Penelitian-penelitian mengenai tacrolimus, sebuah obat yang digunakan untuk mencegah penolakan organ pada pasien transplantasi organ, mengindikasikan bahwa para pasien Amerika keturunan Afrika membutuhkan dosis yang lebih tinggi dari pada mereka yang berkulit putih

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