La revolución de la información en la genética

Averiguar los secretos del genoma humano sería imposible sin la manipulación computadorizada de cantidades ingentes de datos, incluida la mayoría de los tres mil millones de unidades químicas que componen el plan maestro genético de nuestra especie, pero lo que esa revolución de la "bioinformática" ha aportado, por encima de todo, es la confirmación absoluta de la base evolutiva de toda la vida en la Tierra.

Los datos sobre secuencias, ya se refieran a proteínas o a ácidos nucleicos, se prestan muy bien al tratamiento informático, porque son fáciles de digitalizar y descomponer en sus unidades constitutivas. Programas informáticos simples pueden comparar dos o más ristras de dichas unidades y evaluar los grados de similitud, buscar en enormes bases de datos para comparar las nuevas secuencias con las ya conocidas y juntar grupos de secuencias en forma de árbol genealógico.

Las consecuencias de la investigación de las primeras proteínas estudiadas hace casi medio siglo fueron profundas. Todas aquellas secuencias eran bastante pequeñas -la insulina tiene unos cincuenta aminoácidos, según las especies-, pero la variación entre las especies resultaba clara.

To continue reading, please log in or enter your email address.

Registration is quick and easy and requires only your email address. If you already have an account with us, please log in. Or subscribe now for unlimited access.


Log in;
  1. An employee works at a chemical fiber weaving company VCG/Getty Images

    China in the Lead?

    For four decades, China has achieved unprecedented economic growth under a centralized, authoritarian political system, far outpacing growth in the Western liberal democracies. So, is Chinese President Xi Jinping right to double down on authoritarianism, and is the “China model” truly a viable rival to Western-style democratic capitalism?

  2. The assembly line at Ford Bill Pugliano/Getty Images

    Whither the Multilateral Trading System?

    The global economy today is dominated by three major players – China, the EU, and the US – with roughly equal trading volumes and limited incentive to fight for the rules-based global trading system. With cooperation unlikely, the world should prepare itself for the erosion of the World Trade Organization.

  3. Donald Trump Saul Loeb/Getty Images

    The Globalization of Our Discontent

    Globalization, which was supposed to benefit developed and developing countries alike, is now reviled almost everywhere, as the political backlash in Europe and the US has shown. The challenge is to minimize the risk that the backlash will intensify, and that starts by understanding – and avoiding – past mistakes.

  4. A general view of the Corn Market in the City of Manchester Christopher Furlong/Getty Images

    A Better British Story

    Despite all of the doom and gloom over the United Kingdom's impending withdrawal from the European Union, key manufacturing indicators are at their highest levels in four years, and the mood for investment may be improving. While parts of the UK are certainly weakening economically, others may finally be overcoming longstanding challenges.

  5. UK supermarket Waring Abbott/Getty Images

    The UK’s Multilateral Trade Future

    With Brexit looming, the UK has no choice but to redesign its future trading relationships. As a major producer of sophisticated components, its long-term trade strategy should focus on gaining deep and unfettered access to integrated cross-border supply chains – and that means adopting a multilateral approach.

  6. The Year Ahead 2018

    The world’s leading thinkers and policymakers examine what’s come apart in the past year, and anticipate what will define the year ahead.

    Order now