治疗遗传性乳腺癌

十分之一的发达国家女性患有乳腺癌,并且这种疾病在多数这些国家中正呈上升趋势。但是,无论是哪个(或哪些)原因导致了目前这种趋势,我们都知道5%至10%的乳腺癌患者是由于BRCA1或BRCA2基因感染了遗传性缺陷。

携带变异的BRCA1或BRCA2基因的妇女患上乳腺癌的几率约有80%。这些基因内的变异也导致了卵巢肿瘤的发生。

十多年前当人们发现BRCA1和BRCA2基因的时候,人们曾对新的有针对性治疗方案期望甚高。令人失望的是,至今还没有出现任何新治疗方案。结果,那些携带高度变异BRCA1 或BRCA2基因的妇女不得不痛苦地选择手术割除她们的胸部和卵巢以抵抗癌症。

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