Krebs, der zurückkommt

LONDON, ONTARIO – Es ist der Forschung an zwei Fronten zu verdanken, dass Fortschritte gegen viele Arten von Krebs erzielt werden und mehr Patienten länger überleben: Verbesserte Methoden zur Früherkennung und die Entwicklung von Therapien, die effektiver und weniger toxisch sind. Schätzungen zufolge gibt es zurzeit allein in den Vereinigten Staaten mehr als 10 Millionen Menschen, die Krebserkrankungen überlebt haben und ihre Zahl wächst kontinuierlich weiter. Andere Industrieländer weisen ähnliche Statistiken im Verhältnis zur Bevölkerungszahl auf.

Krebstumore, die früh erkannt werden – wenn sie klein sind und die Wahrscheinlichkeit geringer ist, dass sich Metastasen (vom Primärtumor ausgehende Absiedlungen) gebildet haben – sind eher mit lokaler Therapie behandelbar, während eine erfolgreiche Behandlung letztlich unwahrscheinlich ist, wenn sich erst einmal metastatische Tumore entwickeln. Und verbesserte Therapien bedeuten, dass Patienten mit Medikamenten behandelt werden können, die besser funktionieren (und dass Patienten eher die volle notwendige Dosis erhalten).

Doch unsere spektakulären Fortschritte bei der Erkennung und Behandlung von Krebs lassen auch das Problem im Ruhezustand befindlicher Tumore, der so genannten Tumor Dormancy, zunehmend ins Bewusstsein rücken: Ein Patient scheint geheilt, doch dann kehrt der gleiche Krebs nach Jahren oder sogar Jahrzehnten zurück. So ist etwa bei Brustkrebs oder Melanomen 25 Jahre nach der ersten Behandlung ein erneutes Auftreten beobachtet worden.

To continue reading, please log in or enter your email address.

Registration is quick and easy and requires only your email address. If you already have an account with us, please log in. Or subscribe now for unlimited access.

required

Log in

http://prosyn.org/zyJHHBL/de;
  1. Television sets showing a news report on Xi Jinping's speech Anthony Wallace/Getty Images

    Empowering China’s New Miracle Workers

    China’s success in the next five years will depend largely on how well the government manages the tensions underlying its complex agenda. In particular, China’s leaders will need to balance a muscular Communist Party, setting standards and protecting the public interest, with an empowered market, driving the economy into the future.

  2. United States Supreme Court Hisham Ibrahim/Getty Images

    The Sovereignty that Really Matters

    The preference of some countries to isolate themselves within their borders is anachronistic and self-defeating, but it would be a serious mistake for others, fearing contagion, to respond by imposing strict isolation. Even in states that have succumbed to reductionist discourses, much of the population has not.

  3.  The price of Euro and US dollars Daniel Leal Olivas/Getty Images

    Resurrecting Creditor Adjustment

    When the Bretton Woods Agreement was hashed out in 1944, it was agreed that countries with current-account deficits should be able to limit temporarily purchases of goods from countries running surpluses. In the ensuing 73 years, the so-called "scarce-currency clause" has been largely forgotten; but it may be time to bring it back.

  4. Leaders of the Russian Revolution in Red Square Keystone France/Getty Images

    Trump’s Republican Collaborators

    Republican leaders have a choice: they can either continue to collaborate with President Donald Trump, thereby courting disaster, or they can renounce him, finally putting their country’s democracy ahead of loyalty to their party tribe. They are hardly the first politicians to face such a decision.

  5. Angela Merkel, Theresa May and Emmanuel Macron John Thys/Getty Images

    How Money Could Unblock the Brexit Talks

    With talks on the UK's withdrawal from the EU stalled, negotiators should shift to the temporary “transition” Prime Minister Theresa May officially requested last month. Above all, the negotiators should focus immediately on the British budget contributions that will be required to make an orderly transition possible.

  6. Ksenia Sobchak Mladlen Antonov/Getty Images

    Is Vladimir Putin Losing His Grip?

    In recent decades, as President Vladimir Putin has entrenched his authority, Russia has seemed to be moving backward socially and economically. But while the Kremlin knows that it must reverse this trajectory, genuine reform would be incompatible with the kleptocratic character of Putin’s regime.

  7. Right-wing parties hold conference Thomas Lohnes/Getty Images

    Rage Against the Elites

    • With the advantage of hindsight, four recent books bring to bear diverse perspectives on the West’s current populist moment. 
    • Taken together, they help us to understand what that moment is and how it arrived, while reminding us that history is contingent, not inevitable


    Global Bookmark

    Distinguished thinkers review the world’s most important new books on politics, economics, and international affairs.

  8. Treasury Secretary Steven Mnuchin Bill Clark/Getty Images

    Don’t Bank on Bankruptcy for Banks

    As a part of their efforts to roll back the 2010 Dodd-Frank Act, congressional Republicans have approved a measure that would have courts, rather than regulators, oversee megabank bankruptcies. It is now up to the Trump administration to decide if it wants to set the stage for a repeat of the Lehman Brothers collapse in 2008.